S+, S- and S?: Understanding Serological Status and STI Prevention
Definition : « S+ », « S- », « S? » : These are not mathematical or chemical formulas.
- Keywords
- S+, S-, serology, HIV, STD, STI, testing, condom, safe, unsafe, seropo
- Topics
- Sexual Health & Prevention
- Updated

What is S+, S- and S? ?
« S+ », « S- », « S? » : These are not mathematical or chemical formulas. These acronyms indicate a person’s serological status:
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S+ means they are seropositive (HIV positive)
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S- means they are seronegative (HIV negative)
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S? means they do not know their serological status
Why is it important to know your serological status?
We advise you, when you encounter an S? person, to consider them as S+, because in the absence of screening results or medical follow-up, you cannot truly know their serological status.
For S- individuals, know that you cannot necessarily trust your partners either, so you must practice with caution and awareness (see our health section and our advice on this subject)!
The origin and use of the terms S+ and S-
S+ and S- are abbreviations very similar to SMS language and are quite common on forums or chats. Moreover, it avoids using the term “seropo” which generally has a deeply pejorative connotation for the public.
How to manage serological status on our chat?
On our chat, there is no option to openly declare your serological status, in order to avoid any discrimination and internal problems between S- and S+. Your choice regarding condom use is highlighted (safe, unsafe, negotiable unsafe).
S- does not always mean “safe”: Understanding the risks
This is the most important criterion in our eyes when it comes to serology. HIV is not the only STD, and you can very well catch something with an S- if you don’t use a condom. S- does not necessarily mean safe, just as an S+ can have sex with a condom and be safe.
The importance of communication and testing
Anyway, discuss among yourselves, agree on the practices you are looking for and the risks you are willing (or not) to take. But most importantly: take care of each other!
We strongly advise you to get tested for all common STDs and STIs, monitor your health, and consult at the slightest doubt (don’t wait 3 months if you have strange bumps on your genitals, your doctor has seen many penises and we bet he won’t scream or make fun of you when he sees it).